Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756130 | 0.86 | CYP3A4 (0.48) | ABCB1CYP3A4CYP2C9HDAC6POLB | |
| SCHEMBL9756012 | 0.85 | POLB (0.63) | CYP3A4CYP2C9POLB | |
| SCHEMBL9756060 | 0.85 | ABCB1 (0.62) | ABCB1CYP3A4CYP2C9HDAC8HDAC6 | |
| SCHEMBL9755885 | 0.85 | ABCB1 (0.62) | ABCB1CYP3A4CYP2C9HDAC8HDAC6 | |
| SCHEMBL9756413 | 0.84 | ABCB1 (0.67) | ABCB1CYP3A4CYP2C9HDAC8HDAC6 | |
| SCHEMBL9756104 | 0.83 | ABCB1 (0.59) | ABCB1CYP3A4CYP2C9HDAC8HDAC6 | |
| SCHEMBL9756065 | 0.81 | ABCB1 (0.57) | ABCB1CYP3A4CYP2C9HDAC8HDAC6 | |
| SCHEMBL9756180 | 0.81 | ABCB1 (0.74) | ABCB1CYP3A4CYP2C9HDAC8HDAC6 | |
| SCHEMBL9714226 | 0.81 | ABCB1 (0.89) | ABCB1CYP3A4CYP2C9POLB | |
| SCHEMBL9756380 | 0.80 | ABCB1 (0.56) | ABCB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |