Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755921 | 0.99 | CYP3A4 (0.44) | CYP3A4CYP2C9RECQLABCB1POLB | |
| SCHEMBL9756376 | 0.97 | CYP3A4 (0.45) | CYP3A4CYP2C9RECQLABCB1POLB | |
| SCHEMBL9756090 | 0.92 | CYP3A4 (0.47) | CYP3A4CYP2C9RECQLABCB1POLB | |
| SCHEMBL9756372 | 0.88 | ABCB1 (0.53) | CYP3A4CYP2C9ABCB1 | |
| SCHEMBL9756168 | 0.88 | CYP3A4 (0.49) | CYP3A4CYP2C9RECQLABCB1POLB | |
| SCHEMBL9755994 | 0.87 | ABCB1 (0.52) | CYP3A4CYP2C9ABCB1 | |
| SCHEMBL9755951 | 0.87 | POLB (0.53) | CYP3A4CYP2C9RECQLPOLB | |
| SCHEMBL9756455 | 0.85 | POLB (0.52) | CYP3A4CYP2C9RECQLPOLB | |
| SCHEMBL9756062 | 0.85 | ABCB1 (0.54) | CYP3A4CYP2C9ABCB1 | |
| SCHEMBL9755978 | 0.83 | POLB (0.55) | CYP3A4CYP2C9RECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |