Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 8/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124517 | 0.89 | TLR7 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL9125473 | 0.87 | AGTR1 (0.71) | AGTR1AGTR2PPARG | |
| SCHEMBL8394944 | 0.82 | AGTR1 (0.70) | AGTR1AGTR2PPARG | |
| SCHEMBL9122396 | 0.78 | AGTR1 (0.66) | AGTR1AGTR2PPARG | |
| SCHEMBL9756302 | 0.78 | AGTR1 (0.70) | AGTR1AGTR2PPARG | |
| SCHEMBL8396606 | 0.77 | AGTR1 (0.75) | AGTR1AGTR2PPARG | |
| SCHEMBL8089308 | 0.77 | TLR7 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9191552 | 0.76 | PPARG (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL8395682 | 0.75 | AGTR1 (0.72) | AGTR1AGTR2PPARG | |
| SCHEMBL8393824 | 0.74 | AGTR1 (0.70) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461040-A1 | Imidazol derivatives, their process for production, intermediates, their application as medicaments and the pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1991-12-11 | — | — | EP | disclosed |