Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756378 | 0.90 | CYP3A4 (0.53) | CYP3A4CYP2C9ABCB1POLBHDAC1 | |
| SCHEMBL9756403 | 0.90 | CYP3A4 (0.59) | CYP3A4CYP2C9ABCB1POLBHDAC1 | |
| SCHEMBL9714308 | 0.88 | CYP3A4 (0.71) | CYP3A4CYP2C9ABCB1POLBHDAC1 | |
| SCHEMBL9755870 | 0.86 | CYP3A4 (0.49) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL9756032 | 0.86 | ABCB1 (0.74) | CYP3A4CYP2C9ABCB1POLBHDAC6 | |
| SCHEMBL9714496 | 0.85 | POLB (0.73) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL9756507 | 0.85 | CYP3A4 (0.48) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL9756037 | 0.85 | CYP3A4 (0.48) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL9756208 | 0.85 | CYP3A4 (0.48) | CYP3A4CYP2C9ABCB1POLB | |
| SCHEMBL9756298 | 0.84 | POLB (0.74) | CYP3A4CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |