Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17500083 | 0.86 | PTPN22 (0.44) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL28483698 | 0.82 | DNMT1 (0.46) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL33523810 | 0.79 | CES1 (0.42) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL29202921 | 0.79 | CES1 (0.42) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL29787010 | 0.78 | DNMT1 (0.59) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL10533759 | 0.78 | KDM4E (0.44) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL196007 | 0.78 | DNMT1 (0.59) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL29410608 | 0.78 | DNMT1 (0.59) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL702934 | 0.77 | ALDH1A1 (0.50) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR | |
| SCHEMBL29407412 | 0.77 | ALDH1A1 (0.50) | DNMT1ALDH1A1HSD17B10CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991012223-A1 | PROCESS FOR DEHYDROHALOGENATING AROMATIC HALIDES | EASTMAN KODAK COMPANY (US) | 1991-08-22 | — | — | WO | disclosed |
| EP-0442236-A1 | Process for dehydrohalogenating aromatic halides | EASTMAN KODAK COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| CN-1043929-A | The method of dehydrohalogenating aromatic halides | EASTMAN KODAK CO (US) | 1990-07-18 | — | — | CN | disclosed |
| US-4925998-A | RECOVERING HALIDE, GROUP 8 METAL CATALYST | EASTMAN KODAK COMPANY (US) | 1990-05-15 | — | — | US | disclosed |