Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL28255920 | 1.00 | — | — | |
| Ethylene Glycol SCHEMBL27521333 | 0.94 | TSHR (0.75) | TSHRALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| Ethylene Glycol SCHEMBL456374 | 0.94 | — | — | |
| Ethylene Glycol SCHEMBL8590134 | 0.94 | TSHR (0.75) | TSHRALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| Ethylene Glycol SCHEMBL10336621 | 0.94 | TSHR (0.75) | TSHRALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| Ethylene Glycol SCHEMBL27859764 | 0.89 | — | — | |
| Ethylene Glycol SCHEMBL9299266 | 0.89 | — | — | |
| Ethylene Glycol SCHEMBL15477224 | 0.89 | TSHR (0.67) | TSHRALDH1A1SMN1; SMN2LMNAHSD17B10 | |
| Alcohol SCHEMBL10888428 | 0.88 | — | — | |
| Alcohol SCHEMBL377849 | 0.88 | ALDH1A1 (0.86) | TSHRALDH1A1SMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243168-B1 | METHOD FOR PROCESSING SILVER HALIDE PHOTO-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |
| US-4963475-A | HETEROCYCLIC MERCAPTAN ANTIFOGGING AGENTS FOR HIGH-SPEED AND STABLE DEVELOPMENT IN AUTOMATIC EQUIPMENT USING CYANINE PHOTOSENSITIVE DYES, AROMATIC PRIMARY AMINE DEVELOPERS AND A HYDROXYL AMINE PRESERVATIVE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0243168-A2 | Method for processing silver halide photo-sensitive material | KONICA CORPORATION (JP) | 1987-10-28 | — | — | EP | disclosed |