Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756672 | 1.00 | MAPT (0.51) | MAPTMIFPLA2G4ABACE1MAOB | |
| SCHEMBL8942468 | 0.82 | MIF (0.53) | MAPTMIFBACE1LMNAPTGER1 | |
| SCHEMBL8849999 | 0.82 | MIF (0.53) | MAPTMIFBACE1LMNAPTGER1 | |
| SCHEMBL10420189 | 0.80 | AKR1B1 (0.39) | MAPTLMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8915195 | 0.80 | STAT3 (0.45) | BACE1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL10420188 | 0.80 | AKR1B1 (0.39) | MAPTLMNAKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8915201 | 0.80 | STAT3 (0.45) | BACE1LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL5989277 | 0.78 | MAPT (0.57) | MAPTPLA2G4ABACE1MAOBVCAM1 | |
| SCHEMBL5015651 | 0.78 | MAPT (0.57) | MAPTPLA2G4ABACE1MAOBVCAM1 | |
| SCHEMBL5015650 | 0.78 | MAPT (0.57) | MAPTPLA2G4ABACE1MAOBVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011442-A1 | HERBICIDAL CINNAMIC ESTER URACILS | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-08-08 | — | — | WO | disclosed |
| US-4979982-A | Herbicidal cinnamic ester uracils | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-12-25 | — | — | US | disclosed |