Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | XPO1 | O14980 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420188 | 1.00 | AKR1B1 (0.39) | AKR1B1CA12AKR1B10CA1CA2 | |
| SCHEMBL8915201 | 0.83 | STAT3 (0.45) | KMT2AMEN1GAAHPGDDPP4 | |
| SCHEMBL8915195 | 0.83 | STAT3 (0.45) | KMT2AMEN1GAAHPGDDPP4 | |
| SCHEMBL9756672 | 0.80 | MAPT (0.51) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9756670 | 0.80 | MAPT (0.51) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10418843 | 0.80 | CA12 (0.41) | AKR1B1CA12AKR1B10CA1CA2 | |
| SCHEMBL10418844 | 0.80 | CA12 (0.41) | AKR1B1CA12AKR1B10CA1CA2 | |
| SCHEMBL9756705 | 0.79 | CYP1A2 (0.53) | AKR1B1CA12AKR1B10CA1CA2 | |
| SCHEMBL9756703 | 0.79 | CYP1A2 (0.53) | AKR1B1CA12AKR1B10CA1CA2 | |
| SCHEMBL24152418 | 0.76 | CRHBP (0.44) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4979982-A | Herbicidal cinnamic ester uracils | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-12-25 | — | — | US | disclosed |