Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | XPO1 | O14980 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756693 | 1.00 | CA12 (0.47) | CA12AKR1B10CA1CA2AKR1B1 | |
| SCHEMBL7931283 | 0.90 | MAOB (0.38) | CA12AKR1B10CA1CA2AKR1B1 | |
| SCHEMBL6159837 | 0.84 | ALDH1A1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6159834 | 0.84 | ALDH1A1 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19920620 | 0.81 | MAOB (0.32) | CA12AKR1B10CA1CA2AKR1B1 | |
| SCHEMBL10418844 | 0.81 | CA12 (0.41) | CA12AKR1B10CA1CA2AKR1B1 | |
| SCHEMBL10418843 | 0.81 | CA12 (0.41) | CA12AKR1B10CA1CA2AKR1B1 | |
| SCHEMBL4678281 | 0.80 | TTR (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4678277 | 0.80 | TTR (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9756703 | 0.80 | CYP1A2 (0.53) | CA12AKR1B10CA1CA2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011442-A1 | HERBICIDAL CINNAMIC ESTER URACILS | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-08-08 | — | — | WO | disclosed |
| US-4979982-A | Herbicidal cinnamic ester uracils | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-12-25 | — | — | US | disclosed |