Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 2/20 | 0.41 |
| ▸ | SELP | P16109 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756727 | 0.98 | HSD17B10 (0.65) | HSD17B10ALDH1A1KDM4EHPGDLCK | |
| SCHEMBL27548831 | 0.82 | ALDH1A1 (0.70) | HSD17B10ALDH1A1KDM4EHPGDLCK | |
| Sulfosalicylic SCHEMBL6536793 | 0.81 | ALDH1A1 (0.93) | HSD17B10ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL4961094 | 0.81 | HSD17B10 (0.66) | HSD17B10ALDH1A1KDM4EHPGDLCK | |
| SCHEMBL7827859 | 0.81 | HSD17B10 (0.56) | HSD17B10ALDH1A1KDM4EHPGDLCK | |
| Sulfosalicylic SCHEMBL3293226 | 0.81 | ALDH1A1 (0.93) | HSD17B10ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL574220 | 0.80 | HSD17B10 (0.67) | HSD17B10ALDH1A1KDM4EHPGDLCK | |
| SCHEMBL1593800 | 0.80 | ALDH1A1 (0.72) | HSD17B10ALDH1A1KDM4EHPGDLCK | |
| Sulfosalicylic SCHEMBL8592874 | 0.79 | ALDH1A1 (0.89) | HSD17B10ALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11343478 | 0.79 | PHLPP2 (0.63) | HSD17B10ALDH1A1KDM4EHPGDLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077432-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0438752-A1 | Monobactam hydrazides containing catechol sulfonic acid groups | E.R. SQUIBB & SONS, INC. (US) | 1991-07-31 | — | — | EP | disclosed |
| US-5030724-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-07-09 | — | — | US | disclosed |