Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KARS1 | Q15046 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.39 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.39 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL1923113 | 1.00 | CCR1 (0.46) | CCR1CCR5CCR8HRH1SIGMAR1 | |
| Dipyridyl SCHEMBL701722 | 0.99 | CCR1 (0.45) | CCR1CCR5CCR8HRH1SIGMAR1 | |
| Dipyridyl SCHEMBL5004969 | 0.99 | CCR1 (0.45) | CCR1CCR5CCR8HRH1SIGMAR1 | |
| Dipyridyl SCHEMBL3126694 | 0.93 | CCR1 (0.40) | CCR1CCR5CCR8HRH1SIGMAR1 | |
| SCHEMBL6494641 | 0.92 | CCR1 (0.55) | CCR1CCR5CCR8HRH1KARS1 | |
| SCHEMBL6699910 | 0.90 | CCR1 (0.53) | CCR1CCR5CCR8HRH1KARS1 | |
| SCHEMBL7039186 | 0.87 | CCR1 (0.57) | CCR1CCR5CCR8HRH1KARS1 | |
| Dipyridyl SCHEMBL699785 | 0.85 | CCR1 (0.45) | CCR1CCR5CCR8SIGMAR1FAAH | |
| Dipyridyl SCHEMBL5007665 | 0.85 | CCR1 (0.45) | CCR1CCR5CCR8SIGMAR1FAAH | |
| Dipyridyl SCHEMBL8658875 | 0.84 | CCR1 (0.46) | CCR1CCR5CCR8SIGMAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771642-B2 | Active particles for bio-analytical applications and methods for their preparation | Alma Mater Studiorum—Universita' di Bologna (IT) | 2014-07-08 | — | — | US | disclosed |
| US-20110274621-A1 | Active Particles for Bio-Analytical Applications and Methods for Their Preparation | ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA (IT) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274621-A1 | Active Particles for Bio-Analytical Applications and Methods for Their Preparation | PHOSPHO1, LIPA, ALG1 | CCR1 435/4885CCR5 3642/4885CCR8 2392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.