Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PRKCA | P17252 | 4/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.56 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | DGKA | P23743 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756779 | 1.00 | LMNA (0.59) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25902735 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25902757 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25902740 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL19862071 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25902730 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25902733 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL14047346 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25902790 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25902736 | 0.93 | LMNA (0.70) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316374-B1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-31 | — | — | EP | claimed |