Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972145 | 0.81 | CYP2A6 (0.38) | CYP2A6CLK4DYRK1AHDAC4ADRB2 | |
| SCHEMBL1199848 | 0.77 | IDO1 (0.46) | CYP2A6CLK4DYRK1AHDAC4ADRB2 | |
| SCHEMBL13539329 | 0.74 | CYP2A6 (0.48) | CYP2A6CLK4DYRK1AADRB2KAT6A | |
| SCHEMBL1359976 | 0.73 | GRM5 (0.44) | CYP2A6CLK4DYRK1AADRB2KAT6A | |
| SCHEMBL20979817 | 0.73 | CYP2A6 (0.39) | CYP2A6CLK4DYRK1AADRB2GRM5 | |
| SCHEMBL6642380 | 0.73 | NOTUM (0.47) | CYP2A6CLK4DYRK1AADRB2KAT6A | |
| SCHEMBL9756905 | 0.72 | CLK4 (0.47) | CLK4GRM5 | |
| SCHEMBL20456773 | 0.72 | KAT6A (0.36) | CYP2A6CLK4DYRK1AHDAC4KAT6A | |
| SCHEMBL16193051 | 0.71 | NAPRT (0.40) | HDAC4KAT6AVCP | |
| SCHEMBL20033530 | 0.69 | PDE2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030382-A | Liquid crystals | SEIKO EPSON CORPORATION (JP) | 1991-07-09 | — | — | US | disclosed |