SCHEMBL9756905

SCHEMBL9756905

N#Cc1c(F)cc(-c2ncccn2)cc1F

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CLK4 Q9HAZ1 1/20 0.47
TRPV4 Q9HBA0 1/20 0.47
EGLN2 Q96KS0 2/20 0.45
GRM5 P41594 2/20 0.39
SQOR Q9Y6N5 2/20 0.35
CYP11B2 P19099 1/20 0.34
PDE4B Q07343 5/20 0.34
PDE4D Q08499 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4C Q08493 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19557560 0.93 CLK4 (0.42) CLK4TRPV4EGLN2GRM5SQOR
SCHEMBL20033409 0.81 EGLN2 (0.34) CLK4TRPV4EGLN2
SCHEMBL19557567 0.80 EGLN2 (0.34) CLK4TRPV4EGLN2PDE4BPDE4D
SCHEMBL9511667 0.79 TRPV4 (0.42) TRPV4EGLN2CYP11B2
SCHEMBL10532893 0.79 NPC1 (0.53) TRPV4EGLN2CYP11B2
SCHEMBL28136895 0.78 SQOR (0.49) EGLN2GRM5SQOR
SCHEMBL19557546 0.78 EGLN2 (0.45) CLK4TRPV4EGLN2CYP11B2
SCHEMBL244521 0.77 SQOR (0.48) EGLN2GRM5SQOR
SCHEMBL28074923 0.77 SQOR (0.48) EGLN2GRM5SQOR
SCHEMBL12274337 0.77 SQOR (0.48) EGLN2GRM5SQOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030382-A Liquid crystals SEIKO EPSON CORPORATION (JP) 1991-07-09 US claimed
CN-104327832-A Red light organic electrophosphorescent material, preparation method thereof and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2015-02-04 CN disclosed
CN-104327122-A Blue phosphorescent iridium metal complex and preparation method thereof and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2015-02-04 CN disclosed
CN-104327831-A Red light organic electrophosphorescent material, preparation method thereof and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2015-02-04 CN disclosed
CN-104327830-A Red light organic electrophosphorescent material, preparation method thereof and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2015-02-04 CN disclosed
US-5030382-A Liquid crystals SEIKO EPSON CORPORATION (JP) 1991-07-09 US disclosed
US-5030382-A Liquid crystals SEIKO EPSON CORPORATION (JP) 1991-07-09 US disclosed