Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757132 | 0.94 | FFAR1 (0.43) | FFAR1PPARDPPARAF2NR4A2 | |
| SCHEMBL9757175 | 0.91 | TEC (0.37) | FFAR1PPARDPPARAF2RL3NR4A2 | |
| SCHEMBL9757283 | 0.91 | CYSLTR1 (0.38) | F2CYSLTR1 | |
| SCHEMBL9757164 | 0.87 | NR4A2 (0.33) | FFAR1PPARDPPARANR4A2MAOB | |
| SCHEMBL9757135 | 0.86 | TTR (0.34) | MAOA | |
| SCHEMBL9756956 | 0.84 | CYSLTR1 (0.42) | FFAR1PPARDPPARACYSLTR1 | |
| SCHEMBL9757222 | 0.83 | CYSLTR1 (0.35) | CYSLTR1 | |
| SCHEMBL9757039 | 0.82 | PSMB8 (0.46) | FFAR1PPARDPPARAF2NR4A2 | |
| SCHEMBL9757051 | 0.81 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL9756995 | 0.80 | CYSLTR1 (0.47) | FFAR1PPARDPPARAF2RL3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | claimed |
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |
| US-5041453-A | Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |