Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757177 | 0.83 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2ALOX5GPBAR1 | |
| SCHEMBL9635552 | 0.81 | CYSLTR2 (0.54) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL9757185 | 0.79 | CYSLTR1 (0.54) | CYSLTR1CYSLTR2ALOX5GPBAR1 | |
| SCHEMBL9757158 | 0.75 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2ALOX5GPBAR1PPARG | |
| SCHEMBL9761166 | 0.75 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2ALOX5GPBAR1PPARG | |
| SCHEMBL10544504 | 0.73 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9757107 | 0.73 | GPBAR1 (0.51) | CYSLTR1CYSLTR2ALOX5GPBAR1 | |
| SCHEMBL9636955 | 0.71 | CYSLTR2 (0.54) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL9757088 | 0.71 | ALOX5 (0.58) | CYSLTR1CYSLTR2ALOX5GPBAR1 | |
| SCHEMBL14021512 | 0.71 | CYSLTR1 (0.80) | CYSLTR1CYSLTR2ALOX5GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |
| US-5041453-A | Quinolinyl-benzoheterobicyclic derivatives as antagonists of leukotriene D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |