Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757201 | 0.89 | DRD3 (0.74) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9757048 | 0.87 | DRD3 (0.61) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9757443 | 0.84 | DRD3 (0.67) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9757425 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1HPGDHTTHSD17B10 | |
| SCHEMBL9757501 | 0.84 | HPGD (0.56) | DRD3KDM4EALDH1A1HPGDHTT | |
| Pefloxacin SCHEMBL34292 | 0.78 | DRD3 (1.00) | DRD3KDM4EALDH1A1HPGDHTT | |
| Pefloxacin SCHEMBL29351730 | 0.78 | DRD3 (1.00) | DRD3KDM4EALDH1A1HPGDHTT | |
| Pefloxacin SCHEMBL28251251 | 0.78 | DRD3 (1.00) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9757474 | 0.78 | DRD3 (0.64) | DRD3KDM4EALDH1A1HPGDHTT | |
| SCHEMBL11022977 | 0.78 | DRD3 (0.83) | DRD3KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |