Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757249 | 0.89 | KDM4E (0.63) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9757350 | 0.86 | KDM4E (0.53) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL8093551 | 0.85 | TOP2A (0.53) | HPGDKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL9757372 | 0.84 | PIM1 (0.48) | HPGDKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL9757299 | 0.84 | DRD3 (0.64) | HPGDKDM4EHSD17B10ALDH1A1DRD3 | |
| SCHEMBL9757156 | 0.82 | TOP2A (0.47) | HPGDKDM4EHSD17B10ALDH1A1LMNA | |
| SCHEMBL313584 | 0.82 | KDM4E (0.61) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9757327 | 0.79 | KDM4E (0.57) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL312380 | 0.78 | KDM4E (0.84) | HPGDKDM4EHSD17B10ALDH1A1PMP22 | |
| SCHEMBL11185030 | 0.78 | KDM4E (0.71) | HPGDKDM4EHSD17B10ALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |