Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 9/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24588214 | 0.76 | ELANE (0.41) | ELANEMTNR1AMTNR1B | |
| SCHEMBL3817775 | 0.76 | AGPAT2 (0.41) | DAGLAMCL1ELANENR4A2 | |
| SCHEMBL9757021 | 0.75 | MCL1 (0.35) | DAGLAMCL1MTNR1AMTNR1BKAT8 | |
| SCHEMBL3614007 | 0.75 | AGPAT2 (0.41) | DAGLAMCL1ELANENR4A2 | |
| SCHEMBL4791688 | 0.74 | MAOB (0.50) | DAGLANR4A2 | |
| SCHEMBL28009417 | 0.73 | IDO1 (0.40) | DAGLAFAAHELANENR4A2 | |
| SCHEMBL9757019 | 0.72 | PTPN1 (0.38) | — | |
| SCHEMBL30084620 | 0.72 | NR4A2 (0.42) | DAGLAFAAHNR4A2 | |
| SCHEMBL10396515 | 0.71 | BID (0.43) | MCL1NR4A2BIDBCL2L1BAK1 | |
| SCHEMBL2960024 | 0.71 | NR4A2 (0.49) | DAGLANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |