Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757044 | 0.91 | ALDH1A1 (0.30) | HCAR2ALDH1A1GAAHPGDPOLB | |
| SCHEMBL9757423 | 0.72 | DAGLA (0.41) | — | |
| SCHEMBL9757021 | 0.69 | MCL1 (0.35) | HSD17B3ALDH1A1KDM4EGLAGAA | |
| SCHEMBL9757055 | 0.68 | DPP4 (0.43) | ALDH1A1KDM4EGAAMEN1TSHR | |
| SCHEMBL13862920 | 0.61 | PRKCI (0.52) | PTPN1PTPN11ALDH1A1KDM4EGAA | |
| SCHEMBL9739829 | 0.60 | ALOX5 (0.60) | PTPN1PTPN11ALOX5ALDH1A1KDM4E | |
| SCHEMBL13426929 | 0.60 | TSHR (0.38) | PTPN1ALDH1A1KDM4EHIF1AHPGD | |
| SCHEMBL27440129 | 0.60 | HPGD (0.43) | PTPN1PTPN11ALOX5ALDH1A1KDM4E | |
| SCHEMBL28503260 | 0.60 | ALDH1A1 (0.58) | PTPN1PTPN11HCAR2ALDH1A1KDM4E | |
| SCHEMBL9757047 | 0.59 | ALOX5 (0.42) | ALOX5ALDH1A1HTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |