SCHEMBL9757664

SCHEMBL9757664

CCCCCC(C)(C)c1ccc(O)cc1C

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 13/20 0.46
CNR1 P21554 13/20 0.46
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
TYR P14679 2/20 0.40
MEN1 O00255 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX5 P09917 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18704832 0.88 ESR1 (0.42) CNR2CNR1ESR1ESR2TYR
SCHEMBL31553273 0.88 ESR1 (0.42) CNR2CNR1ESR1ESR2TYR
SCHEMBL13637095 0.86 ALOX15 (0.42) ESR1ESR2TYRCYP3A4ALOX15
SCHEMBL2946516 0.85 TYR (0.49) CNR2CNR1ESR1ESR2TYR
SCHEMBL4075420 0.83 ESR1 (0.51) CNR2CNR1ESR1ESR2TYR
SCHEMBL3441329 0.81 TYR (0.53) CNR2CNR1ESR1ESR2TYR
SCHEMBL4403912 0.80 ESR2 (0.42) ESR1ESR2TYRCYP3A4ALOX15
SCHEMBL10898295 0.80 TYR (0.52) CNR2CNR1TYRMEN1TP53
SCHEMBL11516525 0.80 TYR (0.52) CNR2CNR1TYRMEN1TP53
SCHEMBL11654014 0.80 TYR (0.52) CNR2CNR1TYRMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049685-A Nuclear substituted salicylic acids and their salts SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1991-09-17 US disclosed