Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 1.00 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | MC4R | P32245 | 1/20 | 0.58 |
| ▸ | MC3R | P41968 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ractopamine SCHEMBL10659583 | 1.00 | ADRB2 (1.00) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Ractopamine SCHEMBL144797 | 1.00 | ADRB2 (1.00) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Butopamine SCHEMBL122463 | 1.00 | ADRB2 (1.00) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Ractopamine SCHEMBL350754 | 0.98 | ADRB2 (0.97) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Butopamine SCHEMBL11471316 | 0.98 | ADRB2 (0.97) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Ractopamine SCHEMBL8851800 | 0.98 | ADRB2 (0.97) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Ractopamine SCHEMBL11471317 | 0.98 | ADRB2 (0.97) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Butopamine SCHEMBL351104 | 0.98 | ADRB2 (0.97) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Ractopamine SCHEMBL8892153 | 0.98 | ADRB2 (0.97) | ADRB2ADRB3ADRB1CYP3A4MAPK1 | |
| Ractopamine SCHEMBL28884309 | 0.96 | ADRB2 (0.91) | ADRB2ADRB3ADRB1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992473-A | Beta-phenethanolamines | ELI LILLY AND COMPANY (US) | 1991-02-12 | — | — | US | claimed |
| US-4690951-A | B-PHENETHANGLAMINES; FEED EFFICIENCY AND LEANESS | ELI LILLY AND COMPANY (US) | 1987-09-01 | — | — | US | claimed |