Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885484 | 0.93 | KMT2A (0.39) | KMT2AMEN1HSP90AA1SMN1; SMN2TSHR | |
| Acrylonitrile SCHEMBL2775898 | 0.81 | PPARG (0.42) | KMT2AHSP90AA1SMN1; SMN2ALDH1A1MAPT | |
| Acrylonitrile SCHEMBL9503153 | 0.80 | PPARG (0.41) | KMT2AHSP90AA1SMN1; SMN2ALDH1A1MAPT | |
| Acrylonitrile SCHEMBL1275308 | 0.77 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL27857165 | 0.76 | TSHR (0.48) | KMT2AMEN1SMN1; SMN2TSHRMAPT | |
| SCHEMBL28798508 | 0.75 | KDM4E (0.38) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| Acrylic Acid SCHEMBL28074114 | 0.75 | BLM (0.35) | KMT2ATSHRALDH1A1LMNA | |
| Styrene SCHEMBL668985 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2TSHRALDH1A1MAPT | |
| Vinylsulfonic Acid SCHEMBL7905559 | 0.72 | MEN1 (0.35) | KMT2AMEN1TSHRLMNA | |
| Sulfuric Acid SCHEMBL10757867 | 0.72 | BRD4 (0.35) | KMT2AMEN1TSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055503-A | Polysaccharide graft copolymer containing reactive aminoethyl halide group | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-10-08 | — | — | US | disclosed |