Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9758824 | 1.00 | CHRM2 (0.41) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9759028 | 0.93 | MEN1 (0.41) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9759033 | 0.93 | MEN1 (0.41) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9758919 | 0.90 | CHRM2 (0.43) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9758927 | 0.90 | CHRM2 (0.43) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9759606 | 0.89 | BCHE (0.43) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9758855 | 0.89 | BCHE (0.43) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9759096 | 0.89 | CHRM2 (0.41) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9759104 | 0.89 | CHRM2 (0.41) | CHRM2HTR1ACHRM1ADRA1AOPRM1 | |
| SCHEMBL9759408 | 0.89 | CHRM2 (0.48) | CHRM2HTR1ACHRM1ADRA1AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |