Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 5/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.42 |
| ▸ | DRD1 | P21728 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759606 | 1.00 | BCHE (0.43) | BCHECYP2D6TSHRCYP2C19ACHE | |
| SCHEMBL9758828 | 0.89 | CHRM2 (0.41) | BCHECYP2D6TSHRCYP2C19ACHE | |
| SCHEMBL9758824 | 0.89 | CHRM2 (0.41) | BCHECYP2D6TSHRCYP2C19ACHE | |
| SCHEMBL9758919 | 0.88 | CHRM2 (0.43) | BCHECYP2D6TSHRCYP2C19ACHE | |
| SCHEMBL9758927 | 0.88 | CHRM2 (0.43) | BCHECYP2D6TSHRCYP2C19ACHE | |
| SCHEMBL9759405 | 0.87 | CHRM2 (0.48) | BCHECYP2D6TSHRACHECHRM2 | |
| SCHEMBL9759408 | 0.87 | CHRM2 (0.48) | BCHECYP2D6TSHRACHECHRM2 | |
| Hydrochloric Acid SCHEMBL9759113 | 0.86 | CHRM2 (0.41) | BCHECYP2D6TSHRACHECHRM2 | |
| Hydrochloric Acid SCHEMBL9759110 | 0.86 | CHRM2 (0.41) | BCHECYP2D6TSHRACHECHRM2 | |
| SCHEMBL9759028 | 0.85 | MEN1 (0.41) | BCHECYP2D6TSHRCYP2C19ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |