Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757778 | 0.96 | SPHK1 (0.44) | SPHK1ESR2SPHK2 | |
| SCHEMBL9757949 | 0.96 | SPHK1 (0.44) | SPHK1ESR2SPHK2 | |
| SCHEMBL9715891 | 0.96 | SPHK1 (0.44) | SPHK1ESR2SPHK2 | |
| SCHEMBL9758617 | 0.94 | SPHK1 (0.46) | SPHK1ESR2SPHK2 | |
| SCHEMBL9648402 | 0.91 | SPHK1 (0.47) | SPHK1ESR2SPHK2 | |
| SCHEMBL9758199 | 0.91 | SPHK1 (0.47) | SPHK1ESR2SPHK2 | |
| SCHEMBL9716008 | 0.91 | ESR2 (0.38) | SPHK1ESR2SPHK2 | |
| SCHEMBL9716013 | 0.91 | ESR2 (0.38) | SPHK1ESR2SPHK2 | |
| SCHEMBL9759009 | 0.90 | SPHK1 (0.47) | SPHK1ESR2SPHK2 | |
| SCHEMBL9758498 | 0.90 | SPHK1 (0.50) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0154849-A2 | Cyclohexane derivatives | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |