Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648402 | 1.00 | SPHK1 (0.47) | SPHK1SPHK2ESR2S1PR3 | |
| SCHEMBL9646135 | 0.98 | SPHK1 (0.49) | SPHK1SPHK2ESR2S1PR3 | |
| SCHEMBL9649381 | 0.98 | SPHK1 (0.49) | SPHK1SPHK2ESR2S1PR3 | |
| SCHEMBL9757778 | 0.96 | SPHK1 (0.44) | SPHK1SPHK2ESR2S1PR3 | |
| SCHEMBL9715891 | 0.95 | SPHK1 (0.44) | SPHK1SPHK2ESR2 | |
| SCHEMBL9757949 | 0.95 | SPHK1 (0.44) | SPHK1SPHK2ESR2 | |
| SCHEMBL9758617 | 0.94 | SPHK1 (0.46) | SPHK1SPHK2ESR2S1PR3 | |
| SCHEMBL9758911 | 0.91 | SPHK1 (0.42) | SPHK1SPHK2ESR2 | |
| SCHEMBL9759141 | 0.90 | SPHK1 (0.52) | SPHK1SPHK2ESR2 | |
| SCHEMBL9759172 | 0.90 | SPHK1 (0.59) | SPHK1SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |