Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.73 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9059016 | 0.88 | SIGMAR1 (0.58) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| Bicarbonate SCHEMBL9058171 | 0.87 | SIGMAR1 (0.56) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL13935922 | 0.85 | SIGMAR1 (0.71) | SIGMAR1CHRM5CHRM3ALDH1A1SMN1; SMN2 | |
| SCHEMBL19739051 | 0.84 | SIGMAR1 (0.70) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL976125 | 0.84 | SIGMAR1 (1.00) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL25754564 | 0.83 | SIGMAR1 (0.54) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL13661594 | 0.80 | SIGMAR1 (0.64) | SIGMAR1POLBALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1316135 | 0.80 | SIGMAR1 (0.72) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL1314827 | 0.80 | SIGMAR1 (0.72) | SIGMAR1CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL19742394 | 0.80 | SIGMAR1 (0.63) | SIGMAR1ALDH1A1SMN1; SMN2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | claimed |
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |