Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | DRD1 | P21728 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.40 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331892 | 1.00 | ACHE (0.41) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9784839 | 0.94 | BCHE (0.39) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9758135 | 0.92 | MEN1 (0.42) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9758142 | 0.92 | MEN1 (0.42) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9759877 | 0.90 | CHRM2 (0.40) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9759880 | 0.90 | CHRM2 (0.40) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9758598 | 0.89 | BCHE (0.43) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9758590 | 0.89 | BCHE (0.43) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9759318 | 0.88 | CHRM2 (0.47) | ACHECHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9759321 | 0.88 | CHRM2 (0.47) | ACHECHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |