SCHEMBL9759072

SCHEMBL9759072

[CH2]C(O)COC(=O)NCCOC(=O)C(=C)C

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
THRB P10828 1/20 0.41
ACHE P22303 8/20 0.35
LMNA P02545 2/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21671036 0.89 TSHR (0.44) TSHRTHRBACHELMNAMAPK1
SCHEMBL23409634 0.86 TSHR (0.62) TSHRTHRBACHELMNAMAPK1
SCHEMBL275070 0.85 TSHR (0.41) TSHRTHRBACHELMNAMAPK1
SCHEMBL14327215 0.84 TSHR (0.43) TSHRTHRBACHELMNAMAPK1
SCHEMBL17970072 0.84 TSHR (0.40) TSHRTHRBACHELMNAMAPK1
SCHEMBL13872030 0.83 THRB (0.53) TSHRTHRBACHEALDH1A1
SCHEMBL2403793 0.83 THRB (0.53) TSHRTHRBACHEALDH1A1
SCHEMBL23976089 0.83 TSHR (0.42) TSHRTHRBACHELMNAMAPK1
SCHEMBL24354119 0.82 TSHR (0.42) TSHRTHRBACHELMNAMAPK1
SCHEMBL24354124 0.82 THRB (0.50) TSHRTHRBACHELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055377-A LIGHT-SENSITIVE RECORDING ELEMENT AND PROCESS OF FORMING A RELIEF IMAGE WHEREIN THE RECORDING ELEMENT CONTAINS LECITHIN AS AN ADDITIVE BASF AKTIENGESELLSCHAFT (DE) 1991-10-08 US disclosed
US-5035981-A Having a top layer of high-strength, transparent, soluble or swellable polymer containing an antistatic agent of an ethoxylated amine or amide; exposure; development BASF AKTIENGESELLSCHAFT (DE) 1991-07-30 US disclosed
US-4946758-A RELIEF IMAGE FORMING LAYER; HIGH TENSILE STRENGTH POLYMER AND COVERING BASF AKTIENGESELLSCHAFT (DE) 1990-08-07 US disclosed
US-4900795-A PHOTOPOLMERIZABLE POLYMER COMPRISING ETHYLENE, (METH)ACRYLIC ACID AND VINYL OR ACRYLATE MONOMER NEUTRALIZED BY A CYCLIC AMINE OR HYDROXY-CONTAINING AMINE; PHOTORESISTS; PRINTING PLATES; OZONE RESISTANCE; ELONGATION; TENSILE STRENGTH BASF AKTIENGESELLSCHAFT (DE) 1990-02-13 US disclosed