Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759727 | 1.00 | LMNA (0.51) | LMNATP53MEN1KMT2ACNR1 | |
| SCHEMBL9759177 | 0.90 | LMNA (0.39) | LMNATP53MEN1KMT2ACNR1 | |
| SCHEMBL9758863 | 0.90 | LMNA (0.39) | LMNATP53MEN1KMT2ACNR1 | |
| SCHEMBL9759481 | 0.90 | LMNA (0.47) | LMNATP53MEN1KMT2ACNR1 | |
| Hydrochloric Acid SCHEMBL9759734 | 0.90 | LMNA (0.39) | LMNATP53MEN1KMT2ACNR1 | |
| Hydrochloric Acid SCHEMBL9759143 | 0.89 | LMNA (0.47) | LMNATP53MEN1KMT2ACNR1 | |
| SCHEMBL9331559 | 0.85 | LMNA (0.57) | LMNATP53MEN1KMT2ACNR1 | |
| SCHEMBL9759228 | 0.85 | LMNA (0.51) | LMNATP53MEN1KMT2ACNR1 | |
| SCHEMBL9759720 | 0.85 | LMNA (0.51) | LMNATP53MEN1KMT2ACNR1 | |
| Hydrochloric Acid SCHEMBL9331386 | 0.84 | LMNA (0.56) | LMNATP53MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |