Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759287 | 1.00 | BCHE (0.43) | BCHETP53MEN1KMT2ACHRM2 | |
| Hydrochloric Acid SCHEMBL9759812 | 0.99 | BCHE (0.43) | BCHETP53MEN1KMT2ACHRM2 | |
| Hydrochloric Acid SCHEMBL9759816 | 0.99 | BCHE (0.43) | BCHETP53MEN1KMT2ACHRM2 | |
| SCHEMBL9784880 | 0.95 | BCHE (0.41) | BCHETP53MEN1KMT2ACHRM2 | |
| Hydrochloric Acid SCHEMBL9759679 | 0.94 | BCHE (0.40) | BCHETP53MEN1KMT2ACHRM2 | |
| Hydrochloric Acid SCHEMBL9759675 | 0.94 | BCHE (0.40) | BCHETP53MEN1KMT2ACHRM2 | |
| SCHEMBL9784841 | 0.92 | BCHE (0.43) | BCHETP53MEN1KMT2ACHRM2 | |
| SCHEMBL9759479 | 0.92 | LMNA (0.45) | BCHETP53MEN1KMT2ACHRM2 | |
| SCHEMBL9759486 | 0.92 | LMNA (0.45) | BCHETP53MEN1KMT2ACHRM2 | |
| SCHEMBL9784838 | 0.92 | BCHE (0.43) | BCHETP53MEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |