Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784853 | 0.86 | BCHE (0.37) | BCHECYP2D6CYP2C19TSHRACHE | |
| SCHEMBL9784933 | 0.86 | BCHE (0.38) | BCHECYP2D6CYP2C19TSHRACHE | |
| SCHEMBL9784916 | 0.85 | BCHE (0.39) | BCHECYP2D6CYP2C19TSHRACHE | |
| SCHEMBL9784940 | 0.84 | LMNA (0.40) | BCHECYP2D6CYP2C19TSHRACHE | |
| SCHEMBL9784868 | 0.83 | BCHE (0.41) | BCHECYP2D6CYP2C19TSHRACHE | |
| SCHEMBL9758486 | 0.80 | BCHE (0.35) | BCHECYP2D6CYP2C19TSHRACHE | |
| Fumaric Acid SCHEMBL9759384 | 0.78 | BCHE (0.39) | BCHECYP2D6CYP2C19TSHRACHE | |
| Fumaric Acid SCHEMBL9759377 | 0.78 | BCHE (0.39) | BCHECYP2D6CYP2C19TSHRACHE | |
| SCHEMBL9759341 | 0.77 | BCHE (0.37) | BCHEACHEMAPTPOLBGAA | |
| SCHEMBL9759623 | 0.75 | KMT2A (0.38) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |