Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759526 | 1.00 | HTR1A (0.36) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| SCHEMBL9784842 | 1.00 | HTR1A (0.36) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9759006 | 0.99 | HTR1A (0.36) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9759014 | 0.99 | HTR1A (0.36) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9759627 | 0.99 | HTR1A (0.36) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9784872 | 0.99 | HTR1A (0.36) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| SCHEMBL9784854 | 0.92 | BCHE (0.38) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| SCHEMBL9784857 | 0.92 | BCHE (0.38) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9759356 | 0.91 | BCHE (0.37) | HTR1AADRA1ADRD3KCNH2DRD2 | |
| Hydrochloric Acid SCHEMBL9759347 | 0.91 | BCHE (0.37) | HTR1AADRA1ADRD3KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |