Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 7/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.51 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9484846 | 0.86 | PTGER1 (0.62) | ALDH1A1CYSLTR2CYSLTR1RARBLPAR1 | |
| SCHEMBL31746979 | 0.85 | RARB (0.50) | ALDH1A1HSD17B10RARBMEN1RARA | |
| SCHEMBL29133116 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDHSD17B10CYSLTR2CYSLTR1 | |
| SCHEMBL28408449 | 0.81 | PTGS1 (0.66) | LPAR1KMT2AFFAR1FFAR4PTGER1 | |
| SCHEMBL17683883 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL17685355 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL17683870 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL17685382 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL22529051 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10RARBPPARA | |
| SCHEMBL17683857 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDHSD17B10RARBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |