Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447237 | 0.90 | PTGIR (0.57) | PTGIRPTGER2PTGER3PTGER1PTGDR | |
| SCHEMBL11379928 | 0.85 | LMNA (0.49) | PTGIRPTGER2PTGER3PTGER1LMNA | |
| SCHEMBL31055788 | 0.79 | PTGIR (0.62) | PTGIRPTGER2PTGER3PTGER1PTGDR | |
| SCHEMBL4448944 | 0.79 | PTGIR (0.62) | PTGIRPTGER2PTGER3PTGER1PTGDR | |
| SCHEMBL20815456 | 0.79 | PTGIR (0.62) | PTGIRPTGER2PTGER3PTGER1PTGDR | |
| SCHEMBL4093287 | 0.79 | PTGIR (0.62) | PTGIRPTGER2PTGER3PTGER1PTGDR | |
| SCHEMBL11459358 | 0.79 | PTGIR (0.62) | PTGIRPTGER2PTGER3PTGER1PTGDR | |
| SCHEMBL11380702 | 0.78 | PTGIR (0.63) | PTGIRPTGER2PTGER3PTGER1LMNA | |
| SCHEMBL11379011 | 0.78 | PTGIR (0.49) | PTGIRPTGER2PTGER3PTGER1LMNA | |
| SCHEMBL20815454 | 0.77 | PTGIR (0.54) | PTGIRPTGER2PTGER3PTGER1PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023273-A | Antiagglomerants, hypotensive agents, bronchodilators | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-11 | — | — | US | disclosed |