Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760168 | 0.82 | IDO1 (0.39) | CYP3A4FGFR1ALDH1A1MEN1KMT2A | |
| SCHEMBL10580662 | 0.80 | HTT (0.42) | CYP3A4ALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL9193261 | 0.79 | GAA (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL9759953 | 0.74 | IDO1 (0.41) | CYP3A4ALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL9760996 | 0.73 | CYP3A4 (0.40) | CYP3A4ALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL11555544 | 0.72 | KMT2A (0.58) | CYP3A4ALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL9195914 | 0.72 | CYP3A4 (0.38) | CYP3A4FGFR1ALDH1A1MEN1KMT2A | |
| SCHEMBL9195939 | 0.71 | CYP19A1 (0.49) | CYP3A4ALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL10581971 | 0.70 | GRIK1 (0.41) | FGFR1ALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL27999214 | 0.70 | CYP19A1 (0.50) | CYP3A4FGFR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037829-A | Antitumor Activity; Androgen, Estrogen Inhibitors; Suppress The Plasma Elimination Of Retinoids | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-06 | — | — | US | disclosed |