Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.35 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760996 | 0.85 | CYP3A4 (0.40) | IDO1CYP3A4MEN1KMT2ANAMPT | |
| SCHEMBL9195914 | 0.82 | CYP3A4 (0.38) | IDO1CYP3A4MEN1KMT2ANAMPT | |
| SCHEMBL9193015 | 0.79 | CREBBP (0.37) | CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL9760168 | 0.76 | IDO1 (0.39) | IDO1CYP3A4MEN1KMT2AMAPK8 | |
| SCHEMBL10580662 | 0.75 | HTT (0.42) | IDO1CYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL9728652 | 0.75 | CYP19A1 (0.41) | IDO1CYP3A4MEN1KMT2AWNT3A | |
| SCHEMBL9836179 | 0.75 | IDO1 (0.53) | IDO1CYP3A4MEN1KMT2AHTR5A | |
| SCHEMBL8436958 | 0.74 | IDO1 (0.61) | IDO1CYP3A4MEN1KMT2AHTR5A | |
| SCHEMBL9760689 | 0.74 | CYP3A4 (0.39) | IDO1CYP3A4MEN1KMT2AMAPK8 | |
| SCHEMBL9760105 | 0.73 | IDO1 (0.41) | IDO1CYP3A4MEN1KMT2AHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037829-A | Antitumor Activity; Androgen, Estrogen Inhibitors; Suppress The Plasma Elimination Of Retinoids | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-06 | — | — | US | disclosed |