Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | ACR | P10323 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.52 |
| ▸ | RELA | Q04206 | 3/20 | 0.52 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761668 | 0.96 | NPC1 (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9760538 | 0.96 | NPC1 (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9761377 | 0.96 | NPC1 (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9761874 | 0.96 | NPC1 (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9760834 | 0.96 | NPC1 (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9761792 | 0.96 | NPC1 (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9760291 | 0.96 | NPC1 (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9761512 | 0.96 | LMNA (0.56) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9761925 | 0.95 | MAPT (0.53) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9762152 | 0.95 | MAPT (0.53) | LMNANPC1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297745-B1 | OPTICALLY ACTIVE ETHER DERIVATIVES, PREPARATION PROCESSES THEREFOR, LIQUID CRYSTAL MATERIALS AND AN OPTICAL SWITCHING ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-5013479-A | Aromatic ether esters containing two or three benzene rings | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0297745-A1 | Optically active ether derivatives, preparation processes therefor, liquid crystal materials and an optical switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-01-04 | — | — | EP | disclosed |