Cyanazine

Cyanazine

SCHEMBL9760989

CCNc1nc(Cl)nc(NC(C)(C)C#N)n1.O=C(O)CNCP(=O)(O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 4/20 0.46
LMNA P02545 2/20 0.40
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.37
CREBBP Q92793 1/20 0.37
GAA P10253 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.33
MCL1 Q07820 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terbuthylazine SCHEMBL19462952 0.88 KMT2A (0.51) PDE4ALMNAKMT2AALDH1A1CREBBP
Terbuthylazine SCHEMBL29377425 0.88 KMT2A (0.51) PDE4ALMNAKMT2AALDH1A1CREBBP
Simazine SCHEMBL7077279 0.87 LMNA (0.53) PDE4ALMNAKMT2AALDH1A1GAA
Cyanazine SCHEMBL54410 0.80 PDE4A (0.69) PDE4ALMNAKMT2AALDH1A1CREBBP
Cyanazine SCHEMBL8353087 0.80 PDE4A (0.69) PDE4ALMNAKMT2AALDH1A1CREBBP
Cyanazine SCHEMBL7029579 0.80 PDE4A (0.69) PDE4ALMNAKMT2AALDH1A1CREBBP
Cyanazine SCHEMBL29413960 0.80 PDE4A (0.69) PDE4ALMNAKMT2AALDH1A1CREBBP
Atrazine SCHEMBL361723 0.80 GAA (0.45) LMNAALDH1A1CREBBPGAATDP1
Aclonifen SCHEMBL7577094 0.80 TDP1 (0.43) PDE4ALMNAKMT2AGAATDP1
Atrazine SCHEMBL20723473 0.79 GAA (0.44) LMNAALDH1A1CREBBPGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021591-A Herbicides THE DOW CHEMICAL COMPANY (US) 1991-06-04 US disclosed
US-4997940-A Herbicides THE DOW CHEMICAL COMPANY (US) 1991-03-05 US disclosed
US-4992091-A Herbicides THE DOW CHEMICAL COMPANY (US) 1991-02-12 US disclosed
US-4983772-A 2-Methoxy-6-trifluoromethylaniline and 2,6-difluoro-3-methylaniline, intermediates to triazolo/1,5-a/pyrmidine-2-sulfonamide herbicides THE DOW CHEMICAL COMPANY (US) 1991-01-08 US disclosed
US-4954163-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1990-09-04 US disclosed
US-4886883-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1989-12-12 US disclosed
US-4822404-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1989-04-18 US disclosed
US-4818273-A Substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides, compositions containing them, and their utility as herbicides THE DOW CHEMICAL COMPANY (US) 1989-04-04 US disclosed
US-4755212-A Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn THE DOW CHEMICAL COMPANY (US) 1988-07-05 US disclosed
US-4741764-A SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL THE DOW CHEMICAL COMPANY (US) 1988-05-03 US disclosed
US-4740233-A Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil THE DOW CHEMICAL COMPANY (US) 1988-04-26 US disclosed
US-4734123-A HERBICIDE THE DOW CHEMICAL COMPANY (US) 1988-03-29 US disclosed
US-4685958-A Sulfonamides derived from substituted 2-amino-1,2,4-triazolo[1,5-a]-1,3,5-triazines and compositions and methods of controlling undesired vegetation THE DOW CHEMICAL COMPANY (US) 1987-08-11 US disclosed
US-4605433-A 1,2,4-triazolo[1,5-a]-1,3,5-triazine-2-sulfonamides and compositions and methods of controlling undesired vegetation THE DOW CHEMICAL COMPANY (US) 1986-08-12 US disclosed