Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 5/20 | 0.46 |
| ▸ | ARG2 | P78540 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1074893 | 0.86 | FUCA1 (0.38) | ARG1ARG2SLC1A2FUCA1GLA | |
| SCHEMBL1056777 | 0.86 | FUCA1 (0.38) | ARG1ARG2SLC1A2FUCA1GLA | |
| SCHEMBL2033263 | 0.75 | SLC1A2 (0.54) | ARG1ARG2SLC1A2MEN1BLM | |
| SCHEMBL5704293 | 0.75 | SLC1A2 (0.54) | ARG1ARG2SLC1A2MEN1BLM | |
| SCHEMBL2033259 | 0.75 | SLC1A2 (0.54) | ARG1ARG2SLC1A2MEN1BLM | |
| SCHEMBL14216687 | 0.75 | SLC1A2 (0.54) | ARG1ARG2SLC1A2MEN1BLM | |
| SCHEMBL7672628 | 0.75 | SLC1A2 (0.54) | ARG1ARG2SLC1A2MEN1BLM | |
| SCHEMBL2033261 | 0.75 | SLC1A2 (0.54) | ARG1ARG2SLC1A2MEN1BLM | |
| SCHEMBL31345184 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7748836 | 0.73 | SLC1A2 (0.52) | ARG1ARG2SLC1A2MEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448935-A1 | SUBSTITUTED 2-CARBOXAMIDE CYCLOAMINO UREAS | Novartis AG (CH) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011000905-A1 | SUBSTITUTED 2-CARBOXAMIDE CYCLOAMINO UREAS | NOVARTIS AG (CH) | 2011-01-06 | — | — | WO | disclosed |