Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099598 | 0.78 | MAOA (0.42) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL11734711 | 0.76 | TACR2 (0.60) | LMNASMN1; SMN2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL4621810 | 0.76 | TACR2 (0.60) | LMNASMN1; SMN2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL4567002 | 0.75 | MDM2 (0.50) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL8154576 | 0.75 | GCK (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL31464086 | 0.75 | MAOB (0.52) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL27147663 | 0.75 | MAOB (0.52) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL24983810 | 0.74 | MAPT (0.51) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL31588911 | 0.74 | MAPT (0.66) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL10428975 | 0.73 | MAPT (0.43) | LMNASMN1; SMN2L3MBTL1MAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001123-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-03-19 | — | — | US | disclosed |