Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | CCND1 | P24385 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420191 | 0.78 | DYRK1A (0.42) | TSHRHTTMAPTNPC1RAB9A | |
| SCHEMBL12334710 | 0.78 | CCNE2 (0.37) | CCNE2CCNE1CDK2MAPTCCNT1 | |
| SCHEMBL14295795 | 0.77 | MAPT (0.35) | TSHRHTTMAPTNPC1RAB9A | |
| SCHEMBL28581246 | 0.77 | CCNE2 (0.36) | CCNE2CCNE1CDK2HTTMAPT | |
| SCHEMBL25792266 | 0.75 | MAPT (0.40) | TSHRHTTMAPTNPC1RAB9A | |
| SCHEMBL9353447 | 0.75 | TDP1 (0.39) | TSHRHTTMAPTNPC1RAB9A | |
| SCHEMBL9354794 | 0.71 | HTT (0.49) | HTTMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27589197 | 0.71 | MAPT (0.46) | HTTMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9761370 | 0.70 | KDM4E (0.34) | CCNE2CCNE1CDK2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL20702180 | 0.69 | HTT (0.47) | HTTMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |