Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334710 | 0.78 | CCNE2 (0.37) | ALDH1A1MAPT | |
| SCHEMBL10420191 | 0.78 | DYRK1A (0.42) | TDP1ALDH1A1KDM4EPKMADORA2A | |
| SCHEMBL2457899 | 0.77 | MAPT (0.33) | MAPT | |
| SCHEMBL6684736 | 0.77 | ADORA2A (0.42) | TDP1ALDH1A1KDM4EPKMADORA2A | |
| SCHEMBL2542592 | 0.75 | MEN1 (0.39) | TDP1ALDH1A1KDM4EADORA2AADORA2B | |
| Potassium SCHEMBL31289361 | 0.75 | LMNA (0.33) | MAPT | |
| Ammonia Solution, Strong SCHEMBL28953858 | 0.75 | MAPT (0.33) | MAPT | |
| SCHEMBL9761190 | 0.75 | TSHR (0.37) | TDP1ALDH1A1PKMTSHRMAPT | |
| SCHEMBL27825850 | 0.75 | MAPT (0.33) | MAPT | |
| SCHEMBL9762532 | 0.75 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618904-A1 | NOVEL N-PHENYL AMINO PYRAZOLE DERIVATIVES AND MEANS AND PROCESS FOR COLOURING HAIR | Wella Aktiengesellschaft (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994008971-A1 | NOVEL N-PHENYL AMINO PYRAZOLE DERIVATIVES AND MEANS AND PROCESS FOR COLOURING HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |