SCHEMBL9761401

SCHEMBL9761401

CCCCCCCCCCCCCCCCCCCOc1ccc(C(=O)O)cc1N

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.64
HPGD P15428 1/20 0.64
PTPN11 Q06124 2/20 0.63
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
PRSS1 P07477 3/20 0.59
PLA2G4B P0C869 1/20 0.59
PLA2G2D Q9UNK4 1/20 0.59
PLA2G2A P14555 1/20 0.56
NPC1 O15118 1/20 0.56
USP2 O75604 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HSD17B10 Q99714 1/20 0.56
RARB P10826 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8170141 1.00 ALDH1A1 (0.64) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL28318456 0.95 ALDH1A1 (0.58) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL3443299 0.91 CYP1A2 (0.61) ALDH1A1HPGDPTPN11TP53PRSS1
SCHEMBL8170029 0.90 PTPN11 (0.74) ALDH1A1HPGDPTPN11TP53TSHR
Hydrochloric Acid SCHEMBL11788088 0.89 USP2 (0.61) ALDH1A1HPGDTP53PRSS1NPC1
SCHEMBL11600843 0.87 SMPD1 (0.55) ALDH1A1HPGDPRSS1NPC1USP2
SCHEMBL5654276 0.87 CYP1A2 (0.65) ALDH1A1TSHRPRSS1NPC1RAB9A
SCHEMBL8085032 0.86 ALDH1A1 (0.62) ALDH1A1HPGDPTPN11TP53TSHR
SCHEMBL8170977 0.86 CYP1A2 (0.60) ALDH1A1TSHRPRSS1NPC1USP2
SCHEMBL2314260 0.86 CYP1A2 (0.60) ALDH1A1TSHRPRSS1NPC1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4997920-A Dyeing polyolefins CIBA-GEIGY CORPORATION (US) 1991-03-05 US disclosed