Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761642 | 0.86 | PTGS1 (0.30) | PTGS1 | |
| SCHEMBL9621365 | 0.78 | PTGDR (0.35) | — | |
| SCHEMBL9014981 | 0.71 | CHRM1 (0.30) | — | |
| SCHEMBL9014778 | 0.71 | — | — | |
| SCHEMBL9014975 | 0.70 | KDM4E (0.37) | — | |
| SCHEMBL9014946 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL9014942 | 0.67 | — | — | |
| SCHEMBL11002295 | 0.60 | PTGS1 (0.47) | PTGS1SRD5A1ALOX5 | |
| SCHEMBL797506 | 0.59 | SMN1; SMN2 (0.58) | PTGS1ALOX5 | |
| SCHEMBL11221833 | 0.59 | PTGS1 (0.46) | PTGS1SRD5A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001237-A | 2-substituted alkoxy-3-substituted-pyrazines | TOYO JOZO KABUSHIKI KAISHA (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4894453-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | TOYO JOZO KABUSHIKI KAISHA (JP) | 1990-01-16 | — | — | US | disclosed |