Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | AR | P10275 | 12/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17266277 | 0.73 | AR (0.61) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4145551 | 0.71 | LMNA (0.58) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2499085 | 0.71 | NPC1 (0.60) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2698786 | 0.71 | NPC1 (0.60) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4463690 | 0.71 | LMNA (0.68) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24375919 | 0.71 | LMNA (0.58) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20243714 | 0.71 | LMNA (0.58) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18674645 | 0.71 | LMNA (0.71) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1063021 | 0.71 | LMNA (0.54) | LMNAARNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9282405 | 0.70 | LMNA (0.57) | LMNAARNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |