SCHEMBL9761680

SCHEMBL9761680

O=C(Oc1ccc(Oc2ccccc2F)cc1)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.62
KMT2A Q03164 11/20 0.51
MAPT P10636 4/20 0.51
ALDH1A1 P00352 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PKM P14618 1/20 0.51
FAAH O00519 1/20 0.51
LPAR1 Q92633 4/20 0.51
LPAR5 Q9H1C0 4/20 0.51
MEN1 O00255 4/20 0.50
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ATM Q13315 1/20 0.48
CXCL8 P10145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10437240 0.95 PARP10 (0.65) PARP10KMT2AMAPTALDH1A1TDP1
SCHEMBL9762139 0.83 PARP10 (0.71) PARP10FAAHLPAR1LPAR5
SCHEMBL9762927 0.83 KMT2A (0.47) PARP10KMT2AMAPTALDH1A1TDP1
SCHEMBL2464842 0.83 KMT2A (0.65) PARP10KMT2AMAPTALDH1A1TDP1
SCHEMBL1323923 0.83 KMT2A (0.63) PARP10KMT2AMAPTFAAHMEN1
SCHEMBL9809037 0.82 PARP10 (0.69) PARP10KMT2AMAPTALDH1A1TDP1
SCHEMBL9809043 0.82 PARP10 (0.69) PARP10KMT2AMAPTALDH1A1TDP1
SCHEMBL3133651 0.81 PARP10 (0.73) PARP10LPAR1LPAR5
SCHEMBL11149811 0.81 PARP10 (0.67) PARP10KMT2AMAPTALDH1A1TDP1
SCHEMBL28276502 0.81 PARP10 (0.67) PARP10KMT2AMAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5012017-A Peroxide oxidation of halogenated phenoxyphenones to phenoxyophenyl esters, then conversions to phenoxyphenols DOWELANCO (US) 1991-04-30 US disclosed
WO-1990009979-A1 METHODS FOR THE PREPARATION OF BROMINATED INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1990-09-07 WO disclosed
EP-0384043-A2 Methods for the preparation of brominated intermediates THE DOW CHEMICAL COMPANY (US) 1990-08-29 EP disclosed