Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 8/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411879 | 0.88 | CA1 (0.62) | KMT2AALDH1A1LPAR1LPAR5CA1 | |
| SCHEMBL9242685 | 0.85 | RAB9A (0.65) | PARP10KMT2AALDH1A1LPAR1LPAR5 | |
| SCHEMBL15669422 | 0.84 | NPC1 (0.53) | PARP10KMT2AALDH1A1CA1CA2 | |
| SCHEMBL16507371 | 0.84 | LPAR1 (0.79) | LPAR1LPAR5 | |
| SCHEMBL9762806 | 0.83 | PARP10 (0.71) | PARP10LPAR1LPAR5MAPTRAB9A | |
| SCHEMBL16506947 | 0.83 | LPAR1 (0.82) | LPAR1LPAR5 | |
| SCHEMBL10437240 | 0.83 | PARP10 (0.65) | PARP10KMT2AALDH1A1LPAR1LPAR5 | |
| SCHEMBL8782253 | 0.82 | SLC6A3 (0.61) | KMT2AALDH1A1LPAR1LPAR5CA1 | |
| SCHEMBL1191950 | 0.82 | TDP1 (0.68) | KMT2AALDH1A1LPAR1LPAR5CA1 | |
| SCHEMBL24209453 | 0.82 | PARP10 (0.60) | PARP10LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641897-A | Bcl-2 selective depressant and its preparation and use | 北京赛林泰医药技术有限公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109311860-A | For treating or preventing the Xanthone derivative of hepatitis type B virus disease | 豪夫迈·罗氏有限公司 | 2019-02-05 | — | — | CN | disclosed |