Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491201 | 0.84 | HSD17B10 (0.69) | MMEACEMAPTALDH1A1GAA | |
| SCHEMBL10067641 | 0.84 | MME (0.59) | MMEACEMAPTALDH1A1GAA | |
| SCHEMBL31290862 | 0.84 | MME (0.59) | MMEACEMAPTALDH1A1GAA | |
| SCHEMBL12205972 | 0.83 | MME (0.63) | MMEACEMAPTALDH1A1GAA | |
| SCHEMBL18456226 | 0.83 | MME (0.63) | MMEACEMAPTALDH1A1GAA | |
| SCHEMBL4151615 | 0.83 | MME (0.63) | MMEACEMAPTALDH1A1GAA | |
| SCHEMBL8027661 | 0.83 | MME (0.63) | MMEACEMAPTALDH1A1GAA | |
| SCHEMBL27477626 | 0.82 | MME (0.58) | MMEACEMAPTALDH1A1GAA | |
| Benzene SCHEMBL7271414 | 0.81 | ACE (0.61) | MMEACEMAPTALDH1A1GAA | |
| SCHEMBL16452816 | 0.81 | MME (0.61) | MMEACEMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992453-A | Certain thioimidate and amidine insecticides | ICI AMERICAS INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4931448-A | Thiomidate insecticides | ICI AMERICAS INC. (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0317266-A2 | Novel thioimidate and amidine insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |